November 15, 2019

Thomas J. Gibson
Chief Financial Officer
Streamline Health Solutions, Inc.
1175 Peachtree Street, NE, 10th Floor
Atlanta GA, 30361

       Re: Streamline Health Solutions, Inc.
           Registration Statement on Form S-3
           Filed November 7, 2019
           File No. 333-234567

Dear Mr. Gibson:

       This is to advise you that we have not reviewed and will not review your
registration
statement.

        Please refer to Rules 460 and 461 regarding requests for acceleration.
We remind you
that the company and its management are responsible for the accuracy and
adequacy of their
disclosures, notwithstanding any review, comments, action or absence of action
by the staff.

      Please contact Matthew Derby, Staff Attorney, at (202) 551-2224 or, in
his absence, Jan
Woo, Legal Branch Chief, at (202) 551-3453 with any questions.



                                                            Sincerely,

                                                            Division of
Corporation Finance
                                                            Office of
Technology
cc:    David Ghegan